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Showing 1 to 12 of 59 entries
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Regenerative biology of tendon: mechanisms for renewal and repair.

Current molecular biology reports

Dyment NA, Galloway JL.
PMID: 26389023
Curr Mol Biol Rep. 2015 Sep;1(3):124-131. doi: 10.1007/s40610-015-0021-3.

Understanding the molecular and cellular mechanisms underlying tissue turnover and repair are essential towards addressing pathologies in aging, injury and disease. Each tissue has distinct means of maintaining homeostasis and healing after injury. For some, resident stem cell populations...

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Dyment NA, Galloway JL. Regenerative biology of tendon: mechanisms for renewal and repair. Curr Mol Biol Rep. 2015;1(3):124-131doi: 10.1007/s40610-015-0021-3.
Dyment, N. A., & Galloway, J. L. (2015). Regenerative biology of tendon: mechanisms for renewal and repair. Current molecular biology reports, 1(3), 124-131. https://doi.org/10.1007/s40610-015-0021-3
Dyment, Nathaniel A, and Galloway, Jenna L. "Regenerative biology of tendon: mechanisms for renewal and repair." Current molecular biology reports vol. 1,3 (2015): 124-131. doi: https://doi.org/10.1007/s40610-015-0021-3
Dyment NA, Galloway JL. Regenerative biology of tendon: mechanisms for renewal and repair. Curr Mol Biol Rep. 2015 Sep;1(3):124-131. doi: 10.1007/s40610-015-0021-3. PMID: 26389023; PMCID: PMC4570727.
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Osteocytes and Skeletal Pathophysiology.

Current molecular biology reports

Delgado-Calle J, Bellido T.
PMID: 26693137
Curr Mol Biol Rep. 2015 Dec;1(4):157-167. doi: 10.1007/s40610-015-0026-y. Epub 2015 Oct 06.

For many years, osteocytes have been the forgotten bone cells and considered as inactive spectators buried in the bone matrix. We now know that osteocytes detect and respond to mechanical and hormonal stimuli to coordinate bone resorption and bone...

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Delgado-Calle J, Bellido T. Osteocytes and Skeletal Pathophysiology. Curr Mol Biol Rep. 2015;1(4):157-167doi: 10.1007/s40610-015-0026-y.
Delgado-Calle, J., & Bellido, T. (2015). Osteocytes and Skeletal Pathophysiology. Current molecular biology reports, 1(4), 157-167. https://doi.org/10.1007/s40610-015-0026-y
Delgado-Calle, Jesus, and Bellido, Teresita. "Osteocytes and Skeletal Pathophysiology." Current molecular biology reports vol. 1,4 (2015): 157-167. doi: https://doi.org/10.1007/s40610-015-0026-y
Delgado-Calle J, Bellido T. Osteocytes and Skeletal Pathophysiology. Curr Mol Biol Rep. 2015 Dec;1(4):157-167. doi: 10.1007/s40610-015-0026-y. Epub 2015 Oct 06. PMID: 26693137; PMCID: PMC4673661.
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Targeting the Stem Cell Properties of Adult Breast Cancer Cells: Using Combinatorial Strategies to Overcome Drug Resistance.

Current molecular biology reports

Margaryan NV, Seftor EA, Seftor REB, Hendrix MJC.
PMID: 29152453
Curr Mol Biol Rep. 2017 Sep;3(3):159-164. doi: 10.1007/s40610-017-0067-5. Epub 2017 Jul 10.

PURPOSE OF REVIEW: Cancer is a major public health problem worldwide. In aggressive cancers, which are heterogeneous in nature, there exists a paucity of targetable molecules that can be used to predict outcome and response to therapy in patients,...

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Margaryan NV, Seftor EA, Seftor REB, et al. Targeting the Stem Cell Properties of Adult Breast Cancer Cells: Using Combinatorial Strategies to Overcome Drug Resistance. Curr Mol Biol Rep. 2017;3(3):159-164doi: 10.1007/s40610-017-0067-5.
Margaryan, N. V., Seftor, E. A., Seftor, R. E. B., & Hendrix, M. J. C. (2017). Targeting the Stem Cell Properties of Adult Breast Cancer Cells: Using Combinatorial Strategies to Overcome Drug Resistance. Current molecular biology reports, 3(3), 159-164. https://doi.org/10.1007/s40610-017-0067-5
Margaryan, Naira V, et al. "Targeting the Stem Cell Properties of Adult Breast Cancer Cells: Using Combinatorial Strategies to Overcome Drug Resistance." Current molecular biology reports vol. 3,3 (2017): 159-164. doi: https://doi.org/10.1007/s40610-017-0067-5
Margaryan NV, Seftor EA, Seftor REB, Hendrix MJC. Targeting the Stem Cell Properties of Adult Breast Cancer Cells: Using Combinatorial Strategies to Overcome Drug Resistance. Curr Mol Biol Rep. 2017 Sep;3(3):159-164. doi: 10.1007/s40610-017-0067-5. Epub 2017 Jul 10. PMID: 29152453; PMCID: PMC5687579.
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Recent Advances in Retinal Stem Cell Therapy.

Current molecular biology reports

Bhattacharya S, Gangaraju R, Chaum E.
PMID: 29152454
Curr Mol Biol Rep. 2017 Sep;3(3):172-182. doi: 10.1007/s40610-017-0069-3. Epub 2017 Jul 10.

PURPOSE OF REVIEW: Progress in stem cell research for blinding diseases over the past decade is now being applied to patients with retinal degenerative diseases and soon perhaps, glaucoma. However, the field still has much to learn about the...

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Bhattacharya S, Gangaraju R, Chaum E. Recent Advances in Retinal Stem Cell Therapy. Curr Mol Biol Rep. 2017;3(3):172-182doi: 10.1007/s40610-017-0069-3.
Bhattacharya, S., Gangaraju, R., & Chaum, E. (2017). Recent Advances in Retinal Stem Cell Therapy. Current molecular biology reports, 3(3), 172-182. https://doi.org/10.1007/s40610-017-0069-3
Bhattacharya, Sujoy, et al. "Recent Advances in Retinal Stem Cell Therapy." Current molecular biology reports vol. 3,3 (2017): 172-182. doi: https://doi.org/10.1007/s40610-017-0069-3
Bhattacharya S, Gangaraju R, Chaum E. Recent Advances in Retinal Stem Cell Therapy. Curr Mol Biol Rep. 2017 Sep;3(3):172-182. doi: 10.1007/s40610-017-0069-3. Epub 2017 Jul 10. PMID: 29152454; PMCID: PMC5685516.
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Adipose Tissue Residing Progenitors (Adipocyte Lineage Progenitors and Adipose Derived Stem Cells (ADSC).

Current molecular biology reports

Berry R, Rodeheffer MS, Rosen CJ, Horowitz MC.
PMID: 26526875
Curr Mol Biol Rep. 2015 Sep;1(3):101-109. doi: 10.1007/s40610-015-0018-y. Epub 2015 Jul 12.

The formation of brown, white and beige adipocytes have been a subject of intense scientific interest in recent years due to the growing obesity epidemic in the United States and around the world. This interest has led to the...

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Berry R, Rodeheffer MS, Rosen CJ, et al. Adipose Tissue Residing Progenitors (Adipocyte Lineage Progenitors and Adipose Derived Stem Cells (ADSC). Curr Mol Biol Rep. 2015;1(3):101-109doi: 10.1007/s40610-015-0018-y.
Berry, R., Rodeheffer, M. S., Rosen, C. J., & Horowitz, M. C. (2015). Adipose Tissue Residing Progenitors (Adipocyte Lineage Progenitors and Adipose Derived Stem Cells (ADSC). Current molecular biology reports, 1(3), 101-109. https://doi.org/10.1007/s40610-015-0018-y
Berry, Ryan, et al. "Adipose Tissue Residing Progenitors (Adipocyte Lineage Progenitors and Adipose Derived Stem Cells (ADSC)." Current molecular biology reports vol. 1,3 (2015): 101-109. doi: https://doi.org/10.1007/s40610-015-0018-y
Berry R, Rodeheffer MS, Rosen CJ, Horowitz MC. Adipose Tissue Residing Progenitors (Adipocyte Lineage Progenitors and Adipose Derived Stem Cells (ADSC). Curr Mol Biol Rep. 2015 Sep;1(3):101-109. doi: 10.1007/s40610-015-0018-y. Epub 2015 Jul 12. PMID: 26526875; PMCID: PMC4624461.
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Paracrine Signaling by Extracellular Vesicles via Osteoblasts.

Current molecular biology reports

Morhayim J, Rudjito R, van Leeuwen JP, van Driel M.
PMID: 27429899
Curr Mol Biol Rep. 2016;2:48-55. doi: 10.1007/s40610-016-0034-6. Epub 2016 Feb 23.

Extracellular vesicles (EVs), spherical bilayered proteolipids, behave as paracrine effectors since they are released from cells to deliver signals to other cells. They control a diverse range of biological processes by transferring proteins, lipids, and nucleic acids between cells...

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Morhayim J, Rudjito R, van Leeuwen JP, et al. Paracrine Signaling by Extracellular Vesicles via Osteoblasts. Curr Mol Biol Rep. 2016;2:48-55doi: 10.1007/s40610-016-0034-6.
Morhayim, J., Rudjito, R., van Leeuwen, J. P., & van Driel, M. (2016). Paracrine Signaling by Extracellular Vesicles via Osteoblasts. Current molecular biology reports, 248-55. https://doi.org/10.1007/s40610-016-0034-6
Morhayim, Jess, et al. "Paracrine Signaling by Extracellular Vesicles via Osteoblasts." Current molecular biology reports vol. 2 (2016): 48-55. doi: https://doi.org/10.1007/s40610-016-0034-6
Morhayim J, Rudjito R, van Leeuwen JP, van Driel M. Paracrine Signaling by Extracellular Vesicles via Osteoblasts. Curr Mol Biol Rep. 2016;2:48-55. doi: 10.1007/s40610-016-0034-6. Epub 2016 Feb 23. PMID: 27429899; PMCID: PMC4922391.
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Reciprocal regulation of PPARγ and RUNX2 activities in marrow mesenchymal stem cells: Fine balance between p38 MAPK and Protein Phosphatase 5.

Current molecular biology reports

Stechschulte LA, Lecka-Czernik B.
PMID: 29276666
Curr Mol Biol Rep. 2017 Jun;3(2):107-113. doi: 10.1007/s40610-017-0056-8. Epub 2017 Apr 22.

PURPOSE OF REVIEW: Post-translational modifications (PTMs), specifically serine phosphorylation, are essential for determination and tuning up an activity of many proteins, including those that are involved in the control of gene transcription. Transcription factors PPARγ2 and RUNX2 are essential...

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Stechschulte LA, Lecka-Czernik B. Reciprocal regulation of PPARγ and RUNX2 activities in marrow mesenchymal stem cells: Fine balance between p38 MAPK and Protein Phosphatase 5. Curr Mol Biol Rep. 2017;3(2):107-113doi: 10.1007/s40610-017-0056-8.
Stechschulte, L. A., & Lecka-Czernik, B. (2017). Reciprocal regulation of PPARγ and RUNX2 activities in marrow mesenchymal stem cells: Fine balance between p38 MAPK and Protein Phosphatase 5. Current molecular biology reports, 3(2), 107-113. https://doi.org/10.1007/s40610-017-0056-8
Stechschulte, Lance A, and Lecka-Czernik, Beata. "Reciprocal regulation of PPARγ and RUNX2 activities in marrow mesenchymal stem cells: Fine balance between p38 MAPK and Protein Phosphatase 5." Current molecular biology reports vol. 3,2 (2017): 107-113. doi: https://doi.org/10.1007/s40610-017-0056-8
Stechschulte LA, Lecka-Czernik B. Reciprocal regulation of PPARγ and RUNX2 activities in marrow mesenchymal stem cells: Fine balance between p38 MAPK and Protein Phosphatase 5. Curr Mol Biol Rep. 2017 Jun;3(2):107-113. doi: 10.1007/s40610-017-0056-8. Epub 2017 Apr 22. PMID: 29276666; PMCID: PMC5739323.
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The Potential of microRNAs for Stem Cell-based Therapy for Degenerative Skeletal Diseases.

Current molecular biology reports

Budd E, Waddell S, de Andrés MC, Oreffo ROC.
PMID: 29214143
Curr Mol Biol Rep. 2017;3(4):263-275. doi: 10.1007/s40610-017-0076-4. Epub 2017 Oct 23.

PURPOSE OF REVIEW: Degenerative skeletal disorders including osteoarthritis (OA) and osteoporosis (OP) are the result of attenuation of tissue regeneration and lead to painful conditions with limited treatment options. Preventative measures to limit the onset of OA and OP...

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Budd E, Waddell S, de Andrés MC, et al. The Potential of microRNAs for Stem Cell-based Therapy for Degenerative Skeletal Diseases. Curr Mol Biol Rep. 2017;3(4):263-275doi: 10.1007/s40610-017-0076-4.
Budd, E., Waddell, S., de Andrés, M. C., & Oreffo, R. O. C. (2017). The Potential of microRNAs for Stem Cell-based Therapy for Degenerative Skeletal Diseases. Current molecular biology reports, 3(4), 263-275. https://doi.org/10.1007/s40610-017-0076-4
Budd, Emma, et al. "The Potential of microRNAs for Stem Cell-based Therapy for Degenerative Skeletal Diseases." Current molecular biology reports vol. 3,4 (2017): 263-275. doi: https://doi.org/10.1007/s40610-017-0076-4
Budd E, Waddell S, de Andrés MC, Oreffo ROC. The Potential of microRNAs for Stem Cell-based Therapy for Degenerative Skeletal Diseases. Curr Mol Biol Rep. 2017;3(4):263-275. doi: 10.1007/s40610-017-0076-4. Epub 2017 Oct 23. PMID: 29214143; PMCID: PMC5700219.
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Epigenetic Regulation in Prostate Cancer Progression.

Current molecular biology reports

Ruggero K, Farran-Matas S, Martinez-Tebar A, Aytes A.
PMID: 29888169
Curr Mol Biol Rep. 2018;4(2):101-115. doi: 10.1007/s40610-018-0095-9. Epub 2018 Apr 18.

PURPOSE OF REVIEW: An important number of newly identified molecular alterations in prostate cancer affect gene encoding master regulators of chromatin biology epigenetic regulation. This review will provide an updated view of the key epigenetic mechanisms underlying prostate cancer...

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Ruggero K, Farran-Matas S, Martinez-Tebar A, et al. Epigenetic Regulation in Prostate Cancer Progression. Curr Mol Biol Rep. 2018;4(2):101-115doi: 10.1007/s40610-018-0095-9.
Ruggero, K., Farran-Matas, S., Martinez-Tebar, A., & Aytes, A. (2018). Epigenetic Regulation in Prostate Cancer Progression. Current molecular biology reports, 4(2), 101-115. https://doi.org/10.1007/s40610-018-0095-9
Ruggero, Katia, et al. "Epigenetic Regulation in Prostate Cancer Progression." Current molecular biology reports vol. 4,2 (2018): 101-115. doi: https://doi.org/10.1007/s40610-018-0095-9
Ruggero K, Farran-Matas S, Martinez-Tebar A, Aytes A. Epigenetic Regulation in Prostate Cancer Progression. Curr Mol Biol Rep. 2018;4(2):101-115. doi: 10.1007/s40610-018-0095-9. Epub 2018 Apr 18. PMID: 29888169; PMCID: PMC5976687.
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Context-Dependent Function of Myoepithelial Cells in Breast Morphogenesis and Neoplasia.

Current molecular biology reports

Ingthorsson S, Hilmarsdottir B, Kricker J, Magnusson MK, Gudjonsson T.
PMID: 28680803
Curr Mol Biol Rep. 2015;1(4):168-174. doi: 10.1007/s40610-015-0027-x. Epub 2015 Oct 05.

Myoepithelial cells (MEPs) are specialized cells derived from epithelial progenitor cells, yet they also express the contractile machinery of smooth muscle cells. MEPs are prominent in glandular tissues where their function is to help expel secretions generated by the...

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Ingthorsson S, Hilmarsdottir B, Kricker J, et al. Context-Dependent Function of Myoepithelial Cells in Breast Morphogenesis and Neoplasia. Curr Mol Biol Rep. 2015;1(4):168-174doi: 10.1007/s40610-015-0027-x.
Ingthorsson, S., Hilmarsdottir, B., Kricker, J., Magnusson, M. K., & Gudjonsson, T. (2015). Context-Dependent Function of Myoepithelial Cells in Breast Morphogenesis and Neoplasia. Current molecular biology reports, 1(4), 168-174. https://doi.org/10.1007/s40610-015-0027-x
Ingthorsson, Saevar, et al. "Context-Dependent Function of Myoepithelial Cells in Breast Morphogenesis and Neoplasia." Current molecular biology reports vol. 1,4 (2015): 168-174. doi: https://doi.org/10.1007/s40610-015-0027-x
Ingthorsson S, Hilmarsdottir B, Kricker J, Magnusson MK, Gudjonsson T. Context-Dependent Function of Myoepithelial Cells in Breast Morphogenesis and Neoplasia. Curr Mol Biol Rep. 2015;1(4):168-174. doi: 10.1007/s40610-015-0027-x. Epub 2015 Oct 05. PMID: 28680803; PMCID: PMC5487766.
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Role of Sonic Hedgehog Signaling Pathway in Intervertebral Disc Formation and Maintenance.

Current molecular biology reports

Rajesh D, Dahia CL.
PMID: 30687592
Curr Mol Biol Rep. 2018 Dec;4(4):173-179. doi: 10.1007/s40610-018-0107-9. Epub 2018 Oct 24.

A PURPOSE OF REVIEW: The intervertebral discs (IVD) are an essential component of the spine. Degeneration of the discs, commonly due to age or injury, is a leading cause of chronic lower back pain. Despite its high prevalence, there...

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Rajesh D, Dahia CL. Role of Sonic Hedgehog Signaling Pathway in Intervertebral Disc Formation and Maintenance. Curr Mol Biol Rep. 2018;4(4):173-179doi: 10.1007/s40610-018-0107-9.
Rajesh, D., & Dahia, C. L. (2018). Role of Sonic Hedgehog Signaling Pathway in Intervertebral Disc Formation and Maintenance. Current molecular biology reports, 4(4), 173-179. https://doi.org/10.1007/s40610-018-0107-9
Rajesh, Diviya, and Dahia, Chitra Lekha. "Role of Sonic Hedgehog Signaling Pathway in Intervertebral Disc Formation and Maintenance." Current molecular biology reports vol. 4,4 (2018): 173-179. doi: https://doi.org/10.1007/s40610-018-0107-9
Rajesh D, Dahia CL. Role of Sonic Hedgehog Signaling Pathway in Intervertebral Disc Formation and Maintenance. Curr Mol Biol Rep. 2018 Dec;4(4):173-179. doi: 10.1007/s40610-018-0107-9. Epub 2018 Oct 24. PMID: 30687592; PMCID: PMC6345536.
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Molecular Control of Phosphorus Homeostasis and Precision Treatment of Hypophosphatemic Disorders.

Current molecular biology reports

Weber TJ, Quarles LD.
PMID: 31871877
Curr Mol Biol Rep. 2019 Jun;5(2):75-85. doi: 10.1007/s40610-019-0118-1. Epub 2019 Feb 09.

PURPOSE OF REVIEW: Serum phosphorus is maintained in a narrow range by balancing dietary phosphate absorption, influx and efflux of phosphorus from bone and intracellular stores, and renal reabsorption of filtered phosphate. Acute hypophosphatemia, typically caused by transient increases...

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Weber TJ, Quarles LD. Molecular Control of Phosphorus Homeostasis and Precision Treatment of Hypophosphatemic Disorders. Curr Mol Biol Rep. 2019;5(2):75-85doi: 10.1007/s40610-019-0118-1.
Weber, T. J., & Quarles, L. D. (2019). Molecular Control of Phosphorus Homeostasis and Precision Treatment of Hypophosphatemic Disorders. Current molecular biology reports, 5(2), 75-85. https://doi.org/10.1007/s40610-019-0118-1
Weber, Thomas J, and Quarles, L Darryl. "Molecular Control of Phosphorus Homeostasis and Precision Treatment of Hypophosphatemic Disorders." Current molecular biology reports vol. 5,2 (2019): 75-85. doi: https://doi.org/10.1007/s40610-019-0118-1
Weber TJ, Quarles LD. Molecular Control of Phosphorus Homeostasis and Precision Treatment of Hypophosphatemic Disorders. Curr Mol Biol Rep. 2019 Jun;5(2):75-85. doi: 10.1007/s40610-019-0118-1. Epub 2019 Feb 09. PMID: 31871877; PMCID: PMC6927676.
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Showing 1 to 12 of 59 entries